Hinf I polymorphism 3′ to the human β-globin gene detected by the polymerase chain reaction (PCR)
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چکیده
منابع مشابه
Evaluation of G2677T/A polymorphism of MDR1 gene by polymerase chain reaction in Mazandaran province, Iran
The human MDR1 gene encodes for a P-glycoprotein (PGP), which acts as an efflux pump that transports a large variety of substrates from the inside of cells to the outside until protection against xenobiotics. The G2677T/A polymorphism in exon 21 is associated with PGP expression and function in humans. The present study was aimed to determine the frequencies of this polymorphism in a healthy po...
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References: 1) Moos.M. and Gallwitz.D. (1983) EMBO J. 2, 757-761. 2) Weber.J.L. and May.P.E. (1989) Am. J. Hum. Genet. 44, 388-3%. 3) Lowe.T., Sharefkin.J., Yang.S.Q. and Dieffenbach.C.W. (1990) Nucl. Acids Res. 18, 1757-1761. Source/Description: The polymorphic sequence (TG)25 lies m intron IV, 61 bases 5' from the start of exon 5 of the human alpha-cardiac actin gene (1). The sequence was ide...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1989
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/17.6.2376